Ibrutinib-associated Pneumocystis jirovecii pneumonia
نویسندگان
چکیده
منابع مشابه
Pneumocystis jirovecii Pneumonia
Pneumocystis jirovecii (formerly Pneumocystis carinii sp. f. hominis) is an unusual fungus exhibiting pulmonary tropism and a highly defined host specificity. It is generally regarded as an opportunistic microorganism causing severe and often fatal pneumonia in AIDS patients. However, with the currently rising number of patients receiving immunosuppressive therapies for malignancies, allogeneic...
متن کاملAtypical Pneumocystis jirovecii pneumonia in previously untreated patients with CLL on single-agent ibrutinib.
Ibrutinib is not known to confer risk for Pneumocystis jirovecii pneumonia (PCP). We observed 5 cases of PCP in 96 patients receiving single-agent ibrutinib, including 4 previously untreated. Clinical presentations included asymptomatic pulmonary infiltrates, chronic cough, and shortness of breath. The diagnosis was often delayed. Median time from starting ibrutinib to occurrence of PCP was 6 m...
متن کاملAtypical radiographic manifestation in Pneumocystis jirovecii pneumonia
An 88yearold woman with rheumatoid arthritis (RA) was transferred to our hospital due to cough, fever, and hypoxia. She had received 8 mg of weekly methotrexate and 4 mg of daily prednisolone and had not been given Pneumocystis jirovecii pneumonia (PCP) prophylaxis. Her chest Xray showed consolidation of the left lower lung field (Figure 1), and chest computed tomography confirmed left lower lo...
متن کاملPneumocystis jirovecii Pneumonia in AIDS Patients
Jose M. Varela1, Francisco J. Medrano1, Eduardo Dei-Cas2,3 and Enrique J. Calderón1 1Instituto de Biomedicina de Sevilla and CIBER de Epidemiología y Salud Pública, Internal Medicine Service, Virgen del Rocío University Hospital. Seville, 2Parasitology-Mycology Service (EA4547), Centre of Biology Pathology, Lille-2 University Hospital Centre, Faculty of Medicine, Univ. Lille Nord de France, 3Bi...
متن کاملPneumocystis jirovecii pneumonia in developing countries*
Pneumocystis pneumonia (PcP) is a serious fungal infection among immunocompromised patients. In developed countries, the epidemiology and clinical spectrum of PcP have been clearly defined and well documented. However, in most developing countries, relatively little is known about the prevalence of pneumocystosis. Several articles covering African, Asian and American countries were reviewed in ...
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ژورنال
عنوان ژورنال: American Journal of Hematology
سال: 2017
ISSN: 0361-8609
DOI: 10.1002/ajh.24890